AMRC has developed a number of policies on animal research, three of which are mandatory requirements for all members. Overview guidance on implementing these policies can be downloaded here. Specific guidance on each policy is listed below.


  1. Publicly support our statement on the use of animals in research

All AMRC funders must support our position statement on the use of animals in research and must indicate so on their own websites. The statement sets out our support for research using animals where there is no alternative and where there is a clear link between the research and advancing the understanding of disease, preventing disease or developing potential treatments. We have provided some suggested wording to do this and although you don’t have to use these words specifically, they do offer one way to capture the essence of the message of our sector. If you wish, you could of course reproduce the statement directly on your website.

Related guidance documents: 

  1. Consider the 3Rs (replacement, refinement and reduction of animals in research) during peer review

We’ve made it clear that charities funding animal research should consider the 3Rs in their peer review processes. This means that you need to include questions on the 3Rs in your funding application forms and ask peer reviewers to consider the 3Rs as well as making sure they are briefed on the report ‘Responsibility in the use of animals in bioscience research: Expectations of the major research council and charitable funding bodies’. You should also refer grant applications using animals under special protection (non-human primates, cats, dogs, equines) or raising any particular concerns to NC3Rs for additional peer review. Additional questions should be asked when funding animal research overseas.

Related guidance documents:


  1. Provide us with details on the use of animals in our annual data collection

It’s important that we have a good understanding of animal research funding practices across the sector so we have asked all AMRC members to provide three additional pieces of data for each grant reported annually:

  • Are animals protected under UK law used in this project?
  • Which animal species is used?
  • Are any of these animals genetically modified?

We produce an annual animal research briefing using these statistics.

Animals Research Briefing

Good practice

  1. You should consider updating your grant terms and conditions to promote the consideration of the 3Rs by potential applicants. In doing so, you should also include reference to the ARRIVE guidelines and the report ‘Responsibility in the use of animals in bioscience research: Expectations of the major research council and charitable funding bodies’ for reporting research using animals.

Related Guidance Documents:

  1. AMRC has signed the Concordat on openness on animal research and we encourage funders to be open about research they fund that involves animals. It is good practice to do this in the scientific context of what the research has or hopes to achieve and it should be backed up with supporting material explaining why it’s required (e.g. there are no suitable non-animal alternatives). This helps to reassure supporters that this work is not undertaken lightly, and is only done when there are no alternatives.